Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 17/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KIT | P10721 | 1/20 | 0.63 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.63 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.63 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.63 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.63 |
| ▸ | FLT3 | P36888 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664280 | 0.89 | PDGFRB (0.69) | PDGFRBKITFGFR1PDGFRAFGFR2 | |
| SCHEMBL2924358 | 0.82 | PDGFRB (1.00) | PDGFRBKITFGFR1PDGFRAFGFR2 | |
| SCHEMBL2278769 | 0.82 | PDGFRB (1.00) | PDGFRBKITFGFR1PDGFRAFGFR2 | |
| SCHEMBL2912640 | 0.81 | PDGFRB (1.00) | PDGFRBKITFGFR1PDGFRAFGFR2 | |
| SCHEMBL7654089 | 0.80 | PDGFRB (0.76) | PDGFRBKITFGFR1PDGFRAFGFR2 | |
| SCHEMBL1032708 | 0.79 | PDGFRB (1.00) | PDGFRBKITFGFR1PDGFRAFGFR2 | |
| SCHEMBL2921676 | 0.79 | PDGFRB (1.00) | PDGFRBKITFGFR1PDGFRAFGFR2 | |
| SCHEMBL7656560 | 0.79 | PDGFRB (0.74) | PDGFRBKITFGFR1PDGFRAFGFR2 | |
| SCHEMBL7655638 | 0.79 | PDGFRB (0.66) | PDGFRBKITFGFR1PDGFRAFGFR2 | |
| SCHEMBL2922737 | 0.79 | PDGFRB (1.00) | PDGFRBKITFGFR1PDGFRAFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423716-B1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |