Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PRF1 | P14222 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10331963 | 0.77 | SMN1; SMN2 (0.42) | RAB9ANPC1KDM4EMAPTKMT2A | |
| SCHEMBL12722670 | 0.75 | POLB (0.57) | POLBTHRBRECQLTDP1L3MBTL1 | |
| SCHEMBL12529312 | 0.74 | ESRRG (0.61) | POLBTHRBRECQLTDP1L3MBTL1 | |
| SCHEMBL10331952 | 0.74 | HPGD (0.53) | RAB9ANPC1HPGDPIK3CAMTOR | |
| SCHEMBL17029120 | 0.70 | RAB9A (0.58) | POLBRAB9ANPC1KDM4EMAPT | |
| SCHEMBL10332042 | 0.70 | GRIN2B (0.38) | RAB9ANPC1KDM4EMAPTKMT2A | |
| SCHEMBL9668152 | 0.70 | ESRRB (0.59) | POLBTHRBRECQLTDP1L3MBTL1 | |
| SCHEMBL10331956 | 0.68 | MEN1 (0.49) | RAB9ANPC1KMT2AGRIN2B | |
| SCHEMBL1587824 | 0.67 | POLB (0.65) | POLBTHRBRECQLTDP1L3MBTL1 | |
| SCHEMBL10331959 | 0.67 | HDAC4 (0.45) | PRF1RAB9AMAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078015-B1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1 AND/OR NF-KAPPAB ACTIVITY AND USE THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2012-03-21 | — | — | EP | disclosed |