Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654904 | 1.00 | MEN1 (0.50) | MEN1KMT2AMMP8CTDSP1HTR2A | |
| SCHEMBL7490894 | 0.95 | GRIK1 (0.49) | MEN1KMT2AMMP8CTDSP1HTR2A | |
| SCHEMBL9620462 | 0.92 | MMP8 (0.50) | MEN1KMT2AMMP8CTDSP1HTR2A | |
| SCHEMBL9620464 | 0.92 | MMP8 (0.50) | MEN1KMT2AMMP8CTDSP1HTR2A | |
| SCHEMBL28952721 | 0.90 | MEN1 (0.46) | MEN1KMT2AMMP8CTDSP1HTR2A | |
| SCHEMBL12123422 | 0.85 | HTR2A (0.50) | KMT2AHTR2ATDP1PAMGRIK1 | |
| SCHEMBL27629744 | 0.84 | TDP1 (0.52) | MEN1KMT2AMMP8CTDSP1TDP1 | |
| SCHEMBL7309863 | 0.84 | GRIK1 (0.55) | MEN1KMT2ACTDSP1HTR2APAM | |
| Hydrochloric Acid SCHEMBL7309854 | 0.83 | GRIK1 (0.54) | MEN1KMT2ACTDSP1HTR2APAM | |
| Hydrochloric Acid SCHEMBL7309856 | 0.83 | GRIK1 (0.54) | MEN1KMT2ACTDSP1HTR2APAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102875278-B | Method for synthesizing optically-active 2-(2', 3'-allene group) malonate | UNIV ZHEJIANG | 2014-07-30 | — | — | CN | claimed |
| CN-102875278-A | Method for synthesizing optically-active 2-(2', 3'-allene group) malonate | UNIV ZHEJIANG | 2013-01-16 | — | — | CN | claimed |
| CN-114890881-B | Method for simply synthesizing allyl dicarbonyl compound | 南阳师范学院 | 2023-06-02 | — | — | CN | disclosed |
| CN-114890881-A | Method for simply synthesizing allyl dicarbonyl compound | 南阳师范学院 | 2022-08-12 | — | — | CN | disclosed |
| CN-102875278-B | Method for synthesizing optically-active 2-(2', 3'-allene group) malonate | UNIV ZHEJIANG | 2014-07-30 | — | — | CN | disclosed |
| CN-102875278-A | Method for synthesizing optically-active 2-(2', 3'-allene group) malonate | UNIV ZHEJIANG | 2013-01-16 | — | — | CN | disclosed |
| US-6495370-B1 | A METHOD FOR DETECTING A GLUTATHIONE-S-TRANSFERASE ISOENZYME IN A BIOLOGICAL SPECIMEN COMPRISING THE MEASUREMENT OF GLUTATHIONE-S-TRANSFERASE ENZYMATIC ACTIVITY IN THE PRESENCE AND ABSENCE AN AMOUNT OF A COMPOUND OF THE FORMULA HALO | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-12-17 | — | — | US | disclosed |
| US-6103665-A | Inhibition of glutathione transferase by haloenol lactones | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-08-15 | — | — | US | disclosed |
| US-5767147-A | MEDICAL DIAGNOSIS, TREATMENT OF DRUG RESISTANCE IN CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-06-16 | — | — | US | disclosed |
| WO-1996032936-A1 | INHIBITION OF GLUTATHIONE TRANSFERASE BY HALOENOL LACTONES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-10-24 | — | — | WO | disclosed |