Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 6/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756036 | 0.87 | MAPK14 (0.36) | MAPK14NPSR1MEN1KMT2AHPGD | |
| SCHEMBL765758 | 0.86 | CNR2 (0.37) | MAPK14NPSR1MEN1KMT2ACNR2 | |
| SCHEMBL16921577 | 0.81 | NPSR1 (0.36) | MAPK14NPSR1MEN1KMT2ACNR2 | |
| SCHEMBL754114 | 0.80 | CA12 (0.34) | MAPK14NPSR1MEN1KMT2AHPGD | |
| SCHEMBL754113 | 0.80 | CA12 (0.34) | MAPK14NPSR1MEN1KMT2AHPGD | |
| SCHEMBL27756470 | 0.76 | MAPK14 (0.36) | MAPK14NPSR1MEN1KMT2AHPGD | |
| SCHEMBL18531653 | 0.76 | MAPK14 (0.47) | MAPK14NPSR1MEN1KMT2AHPGD | |
| SCHEMBL754083 | 0.74 | LIPG (0.45) | CNR2CNR1GPR55HSP90AA1 | |
| SCHEMBL753713 | 0.73 | MEN1 (0.43) | MAPK14NPSR1MEN1KMT2AHPGD | |
| SCHEMBL754549 | 0.72 | LIPG (0.35) | MEN1KMT2ACNR2CNR1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |