SCHEMBL7655422

SCHEMBL7655422

C=CC(=O)OCCCCCCOc1ccc(C(=O)OC2CC[C@@]3(C)C(=CCC4C3CC[C@@]3(C)C4CC[C@@H]3[C@H](C)CCCC(C)C)C2)cc1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.59
CYP46A1 Q9Y6A2 2/20 0.58
PLA2G2A P14555 1/20 0.55
OSBP P22059 3/20 0.54
USP2 O75604 2/20 0.54
RORC P51449 2/20 0.54
LMNA P02545 1/20 0.54
ABCB1 P08183 1/20 0.54
OSBP2 Q969R2 1/20 0.54
GBA1 P04062 2/20 0.53
UGCG Q16739 2/20 0.53
GBA2 Q9HCG7 2/20 0.53
NR1H3 Q13133 2/20 0.49
NPC1L1 Q9UHC9 3/20 0.48
NPC1 O15118 1/20 0.48
CYP1A2 P05177 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7655418 1.00 POLA1 (0.59) POLA1CYP46A1PLA2G2AOSBPUSP2
SCHEMBL18470121 1.00 POLA1 (0.59) POLA1CYP46A1PLA2G2AOSBPUSP2
SCHEMBL816262 0.94 POLA1 (0.55) POLA1CYP46A1PLA2G2AOSBPUSP2
SCHEMBL19759234 0.93 POLA1 (0.60) POLA1CYP46A1PLA2G2AOSBPUSP2
SCHEMBL7452395 0.93 POLA1 (0.59) POLA1CYP46A1PLA2G2AOSBPUSP2
SCHEMBL7452399 0.93 POLA1 (0.59) POLA1CYP46A1PLA2G2AOSBPUSP2
SCHEMBL19958469 0.92 POLA1 (0.57) POLA1CYP46A1PLA2G2AOSBPUSP2
SCHEMBL5096576 0.91 POLA1 (0.63) POLA1CYP46A1PLA2G2AOSBPUSP2
SCHEMBL5888412 0.91 POLA1 (0.63) POLA1CYP46A1PLA2G2AOSBPUSP2
SCHEMBL5888416 0.91 POLA1 (0.63) POLA1CYP46A1PLA2G2AOSBPUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423865-B1 CROSSLINKING DAIMLERCHRYSLER AG (DE) 2002-07-23 US disclosed
US-6313326-B1 COLORING PAINTS DAIMLERCHRYSLER AG (DE) 2001-11-06 US disclosed
US-6303050-B1 COMPOUNDS OF A DEFINED STRUCTURE CAN BE USED IN A PLANNED MANNER FOR BUILDING UP LIQUID-CRYSTALLINE POLYMERS AND THUS FOR CONTROLLING THE CHARACTERISTICS OF THESE POLYMERS. DAIMLERCHRYSLER AG (DE) 2001-10-16 US disclosed
US-6049000-A Compounds and their application as well as a method of producing liquid crystalline polymers therefrom DAIMLERCHRYSLER AG (DE) 2000-04-11 US disclosed
EP-0869112-A1 Compounds, method for preparing them and preparation of liquid crystal polymers by using these compounds Daimler-Benz Aktiengesellschaft (DE) 1998-10-07 EP disclosed
US-5807497-A CROSSLINKED LIQUID CRYSTALLINE POLYMERS DAIMLER-BENZ AG (DE) 1998-09-15 US disclosed
EP-0760836-B1 EFFECT LACQUER AND LACQUERING, IN PARTICULAR FOR CAR BODIES, BY MEANS OF LIQUID CRYSTAL INTERFERENCE PIGMENTS DAIMLER BENZ AG (DE) 1998-07-29 EP disclosed
EP-0837054-A2 Compounds and their use as well as a process for the preparation of polymeric liquid crystals therefrom Daimler-Benz Aktiengesellschaft (DE) 1998-04-22 EP disclosed
EP-0760836-A1 EFFECT LACQUER AND LACQUERING, IN PARTICULAR FOR CAR BODIES, BY MEANS OF LIQUID CRYSTAL INTERFERENCE PIGMENTS DAIMLER-BENZ AKTIENGESELLSCHAFT (DE) 1997-03-12 EP disclosed
WO-1995032247-A1 EFFECT LACQUER AND LACQUERING, IN PARTICULAR FOR CAR BODIES, BY MEANS OF LIQUID CRYSTAL INTERFERENCE PIGMENTS DAIMLER-BENZ AKTIENGESELLSCHAFT (DE) 1995-11-30 WO disclosed