Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.55 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.54 |
| ▸ | OSBP | P22059 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | RORC | P51449 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
| ▸ | UGCG | Q16739 | 2/20 | 0.47 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.46 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655422 | 0.94 | POLA1 (0.59) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL18470121 | 0.94 | POLA1 (0.59) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL7655418 | 0.94 | POLA1 (0.59) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL19759234 | 0.91 | POLA1 (0.60) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL7670476 | 0.89 | POLA1 (0.61) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL7670481 | 0.89 | POLA1 (0.61) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL8436533 | 0.89 | POLA1 (0.57) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL7452395 | 0.88 | POLA1 (0.59) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL7452399 | 0.88 | POLA1 (0.59) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL17268824 | 0.87 | POLA1 (0.63) | POLA1CYP46A1OSBPUSP2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325168-B1 | POLYMERIZABLE OPTICALLY ACTIVE IMIDE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND | ADEKA CORP (JP) | 2014-03-19 | — | — | EP | disclosed |
| US-8512597-B2 | Polymerizable optically active imide compound and polymerizable composition containing the compound | ADEKA CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| US-8512597-B2 | Polymerizable optically active imide compound and polymerizable composition containing the compound | ADEKA CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| US-8057701-B2 | Trifunctional (meth)acrylate compound and polymerizable composition containing same | ADEKA CORPORATION (JP) | 2011-11-15 | — | — | US | disclosed |
| US-8057701-B2 | Trifunctional (meth)acrylate compound and polymerizable composition containing same | ADEKA CORPORATION (JP) | 2011-11-15 | — | — | US | disclosed |
| EP-2325168-A1 | POLYMERIZABLE OPTICALLY ACTIVE IMIDE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND | Adeka Corporation (JP) | 2011-05-25 | — | — | EP | disclosed |
| US-20110108765-A1 | POLYMERIZABLE OPTICALLY ACTIVE IMIDE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND | ADEKA CORPORATION (JP) | 2011-05-12 | — | — | US | disclosed |
| US-20110108765-A1 | POLYMERIZABLE OPTICALLY ACTIVE IMIDE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND | ADEKA CORPORATION (JP) | 2011-05-12 | — | — | US | disclosed |
| US-20110037025-A1 | TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING SAME | ADEKA CORPORATION (JP) | 2011-02-17 | — | — | US | disclosed |
| US-20110037025-A1 | TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING SAME | ADEKA CORPORATION (JP) | 2011-02-17 | — | — | US | disclosed |
| EP-2261201-A1 | TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND | Adeka Corporation (JP) | 2010-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110108765-A1 | POLYMERIZABLE OPTICALLY ACTIVE IMIDE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND | H1-4, XPO4, F12 | POLA1 905/4885CYP46A1 2911/4885OSBP 4831/4885 |
| US-20110037025-A1 | TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING SAME | PYM1, MT-CO1, MAT1A | POLA1 631/4885CYP46A1 3967/4885OSBP 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.