Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659034 | 1.00 | ACE (0.51) | ACEMMEPREPCA1CA2 | |
| SCHEMBL7655796 | 1.00 | ACE (0.51) | ACEMMEPREPCA1CA2 | |
| SCHEMBL7658633 | 0.91 | CAPN1 (0.47) | ACE | |
| SCHEMBL7658637 | 0.91 | CAPN1 (0.47) | ACE | |
| SCHEMBL7039233 | 0.88 | KDM4E (0.50) | PREP | |
| SCHEMBL7043163 | 0.88 | KDM4E (0.50) | PREP | |
| SCHEMBL7037763 | 0.81 | KDM4E (0.48) | — | |
| SCHEMBL11157038 | 0.80 | ACE (0.59) | ACEMMEPREP | |
| SCHEMBL11166770 | 0.80 | ACE (0.59) | ACEMMEPREP | |
| SCHEMBL3729400 | 0.78 | ACE (0.57) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403561-B1 | DISORDERS ASSOCIATED WITH THE INACTIVATION OR EXCESSIVE DEGRADATION OF CHOLECYSTOKININ; INHIBITING THE ENZYMATIC HYDROLYSIS OF CHOLECYSTOKININ 1-(2(S)-AMINOBUTYRYL)-2(S)-INDOLINECARBOXYLIC ACID | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-06-11 | — | — | US | disclosed |