Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658633 | 1.00 | CAPN1 (0.47) | CAPN1CTSLCTSBCTSKCCR1 | |
| SCHEMBL7655796 | 0.91 | ACE (0.51) | ACE | |
| SCHEMBL7655799 | 0.91 | ACE (0.51) | ACE | |
| SCHEMBL7659034 | 0.91 | ACE (0.51) | ACE | |
| SCHEMBL7037763 | 0.88 | KDM4E (0.48) | CAPN1CTSLCTSBCTSKCCR1 | |
| SCHEMBL3729400 | 0.88 | ACE (0.57) | ACEXIAP | |
| SCHEMBL7269341 | 0.88 | ACE (0.57) | ACEXIAP | |
| SCHEMBL7039233 | 0.80 | KDM4E (0.50) | XIAP | |
| SCHEMBL7043163 | 0.80 | KDM4E (0.50) | XIAP | |
| SCHEMBL13260016 | 0.79 | XIAP (0.54) | CAPN1CTSLCTSBCTSKCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403561-B1 | DISORDERS ASSOCIATED WITH THE INACTIVATION OR EXCESSIVE DEGRADATION OF CHOLECYSTOKININ; INHIBITING THE ENZYMATIC HYDROLYSIS OF CHOLECYSTOKININ 1-(2(S)-AMINOBUTYRYL)-2(S)-INDOLINECARBOXYLIC ACID | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-06-11 | — | — | US | disclosed |