Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387644 | 0.84 | HRH3 (0.34) | HRH3ALDH1A1 | |
| SCHEMBL4394520 | 0.81 | HRH3 (0.37) | HRH3ALDH1A1 | |
| SCHEMBL4383229 | 0.72 | HRH3 (0.39) | HRH3 | |
| SCHEMBL11507005 | 0.68 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL27780 | 0.67 | — | — | |
| SCHEMBL9211858 | 0.67 | HRH3 (0.49) | HRH3 | |
| SCHEMBL13924100 | 0.66 | — | — | |
| SCHEMBL2221307 | 0.66 | — | — | |
| SCHEMBL14651477 | 0.66 | — | — | |
| Ammonia Solution, Strong SCHEMBL1579773 | 0.66 | ALDH1A1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002085861-A1 | IMIDAZOLIDINE COMPOUNDS AND THEIR USE AS CXCR3 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6469002-B1 | COMPOUNDS WHICH MODULATE CHEMOKINE RECEPTOR ACTIVITY AND ARE USEFUL IN TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. | 2002-10-22 | — | — | US | disclosed |
| EP-0413343-B1 | Furan derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-5075301-A | FURAN DERIVATIVES USEFUL FOR THE TREATMENT OF GASTRO-INTESTINAL DISORDERS | KYOWA HAKKO KOGYO, CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |