Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 17/20 | 0.65 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666331 | 0.90 | PDGFRB (0.63) | PDGFRBPDGFRASMN1; SMN2KITNSD2 | |
| Hydrochloric Acid SCHEMBL7655675 | 0.85 | PDGFRB (0.61) | PDGFRBPDGFRASMN1; SMN2TP53 | |
| SCHEMBL2913092 | 0.83 | PDGFRB (0.73) | PDGFRBPDGFRAKIT | |
| SCHEMBL7662019 | 0.81 | PDGFRB (0.60) | PDGFRBPDGFRAKIT | |
| SCHEMBL2917943 | 0.80 | PDGFRB (0.75) | PDGFRBPDGFRAKIT | |
| Hydrochloric Acid SCHEMBL2914698 | 0.80 | PDGFRB (0.75) | PDGFRBPDGFRAKIT | |
| SCHEMBL2916233 | 0.79 | PDGFRB (0.76) | PDGFRBPDGFRAKIT | |
| SCHEMBL2921050 | 0.79 | PDGFRB (0.82) | PDGFRBPDGFRAKIT | |
| SCHEMBL2921329 | 0.79 | PDGFRB (1.00) | PDGFRBPDGFRAKIT | |
| SCHEMBL2921639 | 0.79 | PDGFRB (0.72) | PDGFRBPDGFRAKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423716-B1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |