Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 14/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.61 |
| ▸ | KIT | P10721 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656170 | 0.90 | PDGFRB (0.65) | PDGFRBPDGFRAKITSMN1; SMN2NSD2 | |
| SCHEMBL2912785 | 0.82 | PDGFRB (0.78) | PDGFRBPDGFRAKITMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7655675 | 0.80 | PDGFRB (0.61) | PDGFRBPDGFRASMN1; SMN2TP53MEN1 | |
| SCHEMBL7656072 | 0.79 | PDGFRB (0.67) | PDGFRBPDGFRAKITMEN1KMT2A | |
| SCHEMBL2922247 | 0.78 | PDGFRB (0.78) | PDGFRBPDGFRAKIT | |
| SCHEMBL2922962 | 0.78 | PDGFRB (0.74) | PDGFRBPDGFRAKIT | |
| SCHEMBL2923018 | 0.77 | PDGFRB (1.00) | PDGFRBPDGFRAKIT | |
| SCHEMBL2920825 | 0.76 | PDGFRB (0.79) | PDGFRBPDGFRAKIT | |
| SCHEMBL2919724 | 0.76 | PDGFRB (1.00) | PDGFRBPDGFRAKIT | |
| SCHEMBL2923993 | 0.76 | PDGFRB (1.00) | PDGFRBPDGFRAKITMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423716-B1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |