Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 12/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669506 | 0.98 | CACNA1B (0.66) | CACNA1BKDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7659273 | 0.94 | CACNA1B (0.68) | CACNA1BMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28744261 | 0.92 | CACNA1B (0.59) | CACNA1BKDM4EPOLBADRA2AADRA2B | |
| SCHEMBL7668239 | 0.91 | CACNA1B (0.56) | CACNA1BKDM4EPOLBMEN1ALDH1A1 | |
| SCHEMBL27533242 | 0.88 | CACNA1B (0.53) | CACNA1BKDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL27552807 | 0.86 | CACNA1B (0.59) | CACNA1BADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7665052 | 0.84 | CACNA1B (0.53) | CACNA1BMEN1KMT2AADRA1A | |
| SCHEMBL4495941 | 0.84 | CACNA1B (0.69) | CACNA1BSMN1; SMN2 | |
| SCHEMBL7663847 | 0.83 | CACNA1B (0.65) | CACNA1BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7656853 | 0.82 | CACNA1B (0.53) | CACNA1BMEN1KMT2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350762-B1 | SELECTIVELY INHIBIT THE ACTION OF N-TYPE CALCIUM CHANNEL; | AJINOMOTO CO., INC. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1043314-A1 | NOVEL DIHYDROPYRIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2000-10-11 | — | — | EP | disclosed |