Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | CCR3 | P51677 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502277 | 0.81 | CCR3 (0.58) | GAACCR3ACHEMEN1KMT2A | |
| SCHEMBL7505057 | 0.79 | OPRM1 (0.55) | CCR3MEN1KMT2AOPRM1 | |
| SCHEMBL6153849 | 0.78 | GAA (1.00) | GAACCR3ALDH1A1MEN1KMT2A | |
| SCHEMBL7503617 | 0.78 | CCR3 (0.51) | GAACCR3ACHEMEN1KMT2A | |
| SCHEMBL22549603 | 0.77 | CCR3 (0.77) | GAACCR3ALDH1A1MEN1KMT2A | |
| SCHEMBL2004615 | 0.76 | CCR3 (1.00) | GAACCR3ALDH1A1ACHEMEN1 | |
| SCHEMBL6153469 | 0.76 | GAA (0.80) | GAACCR3ALDH1A1MEN1KMT2A | |
| Fumaric Acid SCHEMBL9253101 | 0.75 | CCR3 (0.60) | GAACCR3ALDH1A1MEN1KMT2A | |
| Fumaric Acid SCHEMBL9253095 | 0.75 | CCR3 (0.60) | GAACCR3ALDH1A1MEN1KMT2A | |
| SCHEMBL7497962 | 0.75 | GAA (0.60) | GAACCR3ALDH1A1ACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492400-B1 | SUCH AS N-(2,5-DIFLUOROPHENYL)-N'-(2-((4-(PHENYLMETHYL)-1 -PIPERIDINYL)METHYL)PHENYL)UREA; PREVENTION OF ASTHMA AND OTHER ALLERGIC DISEASES | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-12-10 | — | — | US | disclosed |