Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.57 |
| ▸ | BCHE | P06276 | 7/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651098 | 0.91 | BCHE (0.60) | ACHEBCHEFAAHABCC4CACNA1F | |
| SCHEMBL7652687 | 0.88 | ACHE (0.62) | ACHEBCHEFAAHABCC4CACNA1F | |
| SCHEMBL7660783 | 0.87 | ACHE (0.65) | ACHEBCHEFAAHABCC4CACNA1F | |
| SCHEMBL7658561 | 0.87 | BCHE (0.57) | ACHEBCHEFAAHABCC4CACNA1F | |
| SCHEMBL9581596 | 0.80 | BCHE (0.62) | ACHEBCHEFAAHABCC4CACNA1F | |
| SCHEMBL7654983 | 0.79 | BCHE (0.78) | ACHEBCHEFAAHABCC4CACNA1F | |
| SCHEMBL7652169 | 0.79 | BCHE (0.56) | ACHEBCHEFAAHABCC4CACNA1F | |
| SCHEMBL7655129 | 0.79 | BCHE (0.64) | ACHEBCHEFAAHABCC4CACNA1F | |
| SCHEMBL7659089 | 0.77 | ACHE (0.62) | ACHEBCHEFAAHABCC4CACNA1F | |
| SCHEMBL7652733 | 0.77 | ACHE (0.70) | ACHEBCHEFAAHABCC4CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413986-B1 | ALZHEIMER'S DISEASE | AVENTIS PHARMACEUTICALS INC. | 2002-07-02 | — | — | US | disclosed |
| EP-0535496-A1 | (1-Indanon-2yl)methylpiperidines, intermediates and a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-04-07 | — | — | EP | disclosed |