SCHEMBL7656563

SCHEMBL7656563

[NH]C(=O)Cc1nc2ccccc2s1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.58
KMT2A Q03164 4/20 0.58
KDM4E B2RXH2 3/20 0.58
MEN1 O00255 3/20 0.58
GAA P10253 3/20 0.58
SMN1; SMN2 Q16637 6/20 0.56
CYP1A2 P05177 3/20 0.56
CYP2C19 P33261 3/20 0.56
ALOX15 P16050 2/20 0.56
HTT P42858 1/20 0.56
UBE2T Q9NPD8 1/20 0.56
ASIC3 Q9UHC3 1/20 0.56
RAB9A P51151 4/20 0.56
NPC1 O15118 4/20 0.56
TSHR P16473 2/20 0.56
TP53 P04637 1/20 0.56
CASP1 P29466 1/20 0.56
HSD17B10 Q99714 1/20 0.56
HPGD P15428 6/20 0.55
ALDH1A1 P00352 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3684279 0.84 MAPT (0.60) MAPTKMT2AKDM4EMEN1GAA
SCHEMBL1612659 0.84 SMN1; SMN2 (0.67) MAPTKMT2AKDM4EMEN1GAA
SCHEMBL5401254 0.83 MAPT (0.58) MAPTKMT2AKDM4EMEN1GAA
SCHEMBL1398257 0.83 MAPT (0.67) MAPTKMT2AKDM4EMEN1GAA
SCHEMBL1248387 0.83 MAPT (0.58) MAPTKMT2AKDM4EMEN1GAA
Bromide SCHEMBL3868424 0.83 SMN1; SMN2 (0.65) MAPTKMT2AKDM4EMEN1GAA
SCHEMBL77032 0.83 KMT2A (0.68) MAPTKMT2AKDM4EMEN1GAA
SCHEMBL3428629 0.81 MAPT (0.61) MAPTKMT2AKDM4EMEN1GAA
SCHEMBL25005849 0.80 MAPT (0.59) MAPTKMT2AKDM4EMEN1GAA
SCHEMBL19031392 0.80 SMN1; SMN2 (0.57) MAPTKMT2AKDM4EMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337176-B1 COLOR REPRODUCTION AND SHARPNESS; RAPID PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 2002-01-08 US claimed
US-6337176-B1 COLOR REPRODUCTION AND SHARPNESS; RAPID PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 2002-01-08 US disclosed
US-5077182-A Cyan/magenta/yellow couplers having specific spectral sensitometric properties; negative interlayer effect; color reproduction; graininess; image sharpness FUJI PHOTO FILM CO., LTD. (JP) 1991-12-31 US disclosed