Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 14/20 | 0.67 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982416 | 0.78 | CXCR2 (0.94) | CXCR2 | |
| SCHEMBL4965756 | 0.75 | MEN1 (0.50) | CXCR2 | |
| SCHEMBL6973283 | 0.72 | CXCR2 (1.00) | CXCR2 | |
| SCHEMBL7649050 | 0.72 | KDM4E (0.47) | CXCR2ADORA3 | |
| SCHEMBL6971042 | 0.71 | CXCR2 (0.88) | CXCR2 | |
| SCHEMBL6972260 | 0.71 | CXCR2 (0.81) | CXCR2 | |
| SCHEMBL6971239 | 0.71 | CXCR2 (0.81) | CXCR2 | |
| SCHEMBL7650665 | 0.70 | KDM4E (0.64) | — | |
| SCHEMBL17735333 | 0.69 | CXCR2 (0.53) | CXCR2ADORA3 | |
| SCHEMBL6978467 | 0.69 | CXCR2 (1.00) | CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |