Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656605 | 0.75 | CXCR2 (0.67) | CXCR2 | |
| SCHEMBL7649050 | 0.74 | KDM4E (0.47) | MEN1KMT2AADORA2BCXCR2ADORA2A | |
| SCHEMBL4965760 | 0.71 | ADORA2B (0.48) | MEN1KMT2AADORA2BADORA2AKDM4E | |
| SCHEMBL7654106 | 0.69 | MGLL (0.44) | MEN1KMT2AADORA2BCXCR2ADORA2A | |
| SCHEMBL8741446 | 0.67 | CXCR2 (0.47) | MEN1KMT2AADORA2BCXCR2KDM4E | |
| SCHEMBL7658198 | 0.67 | KDM4E (0.44) | MEN1KMT2AADORA2BCXCR2ADORA2A | |
| SCHEMBL23400900 | 0.67 | MEN1 (1.00) | MEN1KMT2AADORA2BADORA2AKDM4E | |
| SCHEMBL23398967 | 0.67 | MEN1 (0.52) | MEN1KMT2AADORA2BADORA2AKDM4E | |
| SCHEMBL7650665 | 0.66 | KDM4E (0.64) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5328859 | 0.66 | PDE4A (0.43) | KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008106202-A1 | THERAMUTEIN MODULATORS | HOUSEY GERARD M (US) | 2008-09-04 | — | — | WO | disclosed |