Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815481 | 0.88 | GAA (0.55) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7589803 | 0.82 | CA1 (0.47) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7569739 | 0.82 | ESRRG (0.44) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL6814663 | 0.79 | RAB9A (0.47) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7645916 | 0.79 | SMN1; SMN2 (0.52) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7568746 | 0.79 | DPP4 (0.42) | GAALMNAALDH1A1MAPTHPGD | |
| SCHEMBL6816088 | 0.79 | TRPV1 (0.46) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL6815179 | 0.78 | ESRRG (0.47) | ALDH1A1 | |
| SCHEMBL7686271 | 0.78 | HDAC3 (0.50) | KMT2AMEN1GAALMNAALDH1A1 | |
| SCHEMBL7570611 | 0.77 | ESRRG (0.35) | LMNASMN1; SMN2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407249-B1 | COMPOUNDS CONTAINING FURAN RING STRUCTURE | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |