Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.46 |
| ▸ | KDR | P35968 | 6/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654391 | 0.80 | HTR2C (0.67) | TRPV1KDRHTR2CHTR2BMEN1 | |
| SCHEMBL6297826 | 0.73 | KDR (0.65) | TRPV1KDRMEN1MAPTKMT2A | |
| SCHEMBL4556067 | 0.73 | KDR (0.75) | TRPV1KDRMEN1KMT2ALMNA | |
| SCHEMBL13906661 | 0.72 | NPC1 (0.69) | TRPV1KDRMEN1MAPTKMT2A | |
| SCHEMBL11003208 | 0.72 | MEN1 (0.61) | TRPV1KDRMEN1MAPTKMT2A | |
| SCHEMBL14783804 | 0.69 | NPC1 (0.55) | TRPV1KDRMEN1MAPTKMT2A | |
| SCHEMBL29591422 | 0.69 | NPC1 (0.55) | TRPV1KDRMEN1MAPTKMT2A | |
| SCHEMBL29591528 | 0.69 | NPC1 (0.53) | TRPV1MEN1KMT2AALDH1A1BRAF | |
| SCHEMBL14783521 | 0.69 | NPC1 (0.53) | TRPV1MEN1KMT2AALDH1A1BRAF | |
| SCHEMBL30413950 | 0.69 | KDR (0.67) | TRPV1KDRMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | claimed |
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | disclosed |