Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 12/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059787 | 0.84 | NAMPT (0.40) | NAMPTHCRTR1C3AR1FNTAFNTB | |
| SCHEMBL7058802 | 0.70 | TSHR (0.41) | C3AR1 | |
| Hydrochloric Acid SCHEMBL7053243 | 0.70 | NAMPT (0.46) | NAMPTGPR183 | |
| Hydrochloric Acid SCHEMBL7053241 | 0.70 | NAMPT (0.46) | NAMPTGPR183 | |
| SCHEMBL7346270 | 0.70 | ALDH1A1 (0.43) | — | |
| SCHEMBL26186284 | 0.67 | NPC1 (0.46) | NAMPTC3AR1CYP3A4CYP2C9MAPT | |
| SCHEMBL7056073 | 0.67 | SMN1; SMN2 (0.36) | HCRTR1MAPT | |
| SCHEMBL7055293 | 0.66 | HCRTR1 (0.37) | HCRTR1 | |
| SCHEMBL7057786 | 0.66 | MCHR1 (0.36) | HCRTR1MAPT | |
| SCHEMBL7059076 | 0.66 | SMN1; SMN2 (0.36) | HCRTR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489324-B2 | TREATING STROKE, ARHTRITIS, CANCER, TISSUE ULCERATION, DECUBITIS ULCER, RESTENOSIS, PERIODONTAL DISEASE, EPIDERMOLYSIS BULLOSA, SCLERITIS, PSORIASIS, AIDS, SEPSIS, AND SEPTIC SHOCK. | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-03 | — | — | US | disclosed |