Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 2/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | FASN | P49327 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3457697 | 0.77 | MAPK14 (0.57) | MAPK14LMNAMAPTL3MBTL1MGLL | |
| SCHEMBL13127708 | 0.75 | MAPK14 (0.55) | MAPK14LMNAMAPTL3MBTL1MGLL | |
| SCHEMBL415352 | 0.74 | SLC6A2 (0.46) | MAPK14LMNAMAPTL3MBTL1CNR1 | |
| SCHEMBL4818082 | 0.73 | MAPK14 (0.54) | MAPK14LMNAMAPTL3MBTL1MGLL | |
| SCHEMBL762616 | 0.73 | MAPK14 (0.57) | MAPK14LMNAMAPTL3MBTL1MGLL | |
| SCHEMBL4818069 | 0.73 | MAPK14 (0.54) | MAPK14LMNAMAPTL3MBTL1MGLL | |
| SCHEMBL443982 | 0.73 | TSHR (0.49) | MAPK14LMNAMAPTL3MBTL1CNR1 | |
| Fluorobenzene SCHEMBL27500625 | 0.73 | MAPK14 (0.69) | MAPK14LMNAMAPTL3MBTL1MGLL | |
| SCHEMBL22216386 | 0.73 | LMNA (0.56) | MAPK14LMNAMAPTL3MBTL1MGLL | |
| SCHEMBL8534513 | 0.72 | MAPK14 (0.64) | MAPK14LMNAMGLLGHSRDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001056974-A2 | INHA INHIBITORS AND THEIR USE AS ANTIBACTERIALS | GENZYME CORPORATION (US) | 2001-08-09 | — | — | WO | claimed |
| US-6372752-B1 | ENZYME INHIBITORS, RESPIRATORY SYSTEM DISORDERS, TUBERCULOSIS AND MYCOBACTERIUM BACTERICIDES | GENZYME CORPORATION | 2002-04-16 | — | — | US | disclosed |
| WO-2001056974-A2 | INHA INHIBITORS AND THEIR USE AS ANTIBACTERIALS | GENZYME CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |