Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657362 | 1.00 | PAM (0.53) | PAMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7571411 | 0.86 | AKT1 (0.62) | PAMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19452350 | 0.86 | AKT1 (0.62) | PAMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9419457 | 0.84 | MEN1 (0.51) | PAMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL827395 | 0.84 | EGFR (0.52) | PAMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9419458 | 0.84 | MEN1 (0.51) | PAMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL827396 | 0.84 | EGFR (0.52) | PAMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13631648 | 0.84 | MEN1 (0.51) | PAMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3154424 | 0.83 | PAM (0.47) | PAMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28044574 | 0.83 | PAM (0.47) | PAMHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11865374-B2 | Functionalized polymers | EVONIK OPERATIONS GMBH (DE) | 2024-01-09 | — | — | US | claimed |
| US-20230312791-A1 | FUNCTIONALIZED POLYMERS | EVONIK OPERATIONS GMBH (DE) | 2023-10-05 | — | — | US | claimed |
| EP-4200343-A1 | FUNCTIONALIZED POLYMERS | Evonik Operations GmbH (DE) | 2023-06-28 | — | — | EP | claimed |
| WO-2022038054-A1 | FUNCTIONALIZED POLYMERS | EVONIK OPERATIONS GMBH (DE) | 2022-02-24 | — | — | WO | claimed |
| EP-3957659-A1 | FUNCTIONALIZED POLYMERS | Evonik Operations GmbH (DE) | 2022-02-23 | — | — | EP | claimed |
| EP-3710503-B1 | FUNCTIONALIZED POLYMERS | EVONIK OPERATIONS GMBH (DE) | 2022-01-05 | — | — | EP | claimed |
| US-20200383896-A1 | FUNCTIONALIZED POLYMERS | EVONIK OPERATIONS GMBH (DE) | 2020-12-10 | — | — | US | claimed |
| EP-3710503-A1 | FUNCTIONALIZED POLYMERS | Evonik Degussa GmbH (DE) | 2020-09-23 | — | — | EP | claimed |
| CN-111356710-A | Functionalized polymers | 赢创运营有限公司 | 2020-06-30 | — | — | CN | claimed |
| US-4618647-A | TWO POLYMERIZATION CATALYSTS | UNION CARBIDE CORP. (US) | 1986-10-21 | — | — | US | claimed |
| US-11865374-B2 | Functionalized polymers | EVONIK OPERATIONS GMBH (DE) | 2024-01-09 | — | — | US | disclosed |
| US-20230312791-A1 | FUNCTIONALIZED POLYMERS | EVONIK OPERATIONS GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| EP-4200343-A1 | FUNCTIONALIZED POLYMERS | Evonik Operations GmbH (DE) | 2023-06-28 | — | — | EP | disclosed |
| CN-111356710-B | Functionalized polymers | 赢创运营有限公司 | 2022-04-26 | — | — | CN | disclosed |
| WO-2022038054-A1 | FUNCTIONALIZED POLYMERS | EVONIK OPERATIONS GMBH (DE) | 2022-02-24 | — | — | WO | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| US-4727110-A | TWO-STAGE; POLYMER AS STABILIZER | UNION CARBIDE CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4618647-A | TWO POLYMERIZATION CATALYSTS | UNION CARBIDE CORP. (US) | 1986-10-21 | — | — | US | disclosed |
| US-4066524-A | IMIDAZOLE POLYMERS AND PREPARATION THEREOF WITH RADIATION AND CHEMICAL INITIATOR | HERCULES INCORPORATED (US) | 1978-01-03 | — | — | US | disclosed |
| US-3948740-A | Polymerization of water soluble monomers with radiation and chemical initiator | HERCULES INCORPORATED (US) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11865374-B2 | Functionalized polymers | PUF60, PARN, PARG | PAM 150/4885HDAC3 1672/4885HDAC4 2353/4885 |
| US-20200383896-A1 | FUNCTIONALIZED POLYMERS | PUF60, PARN, PARG | PAM 150/4885HDAC3 1672/4885HDAC4 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.