Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | PYGL | P06737 | 4/20 | 0.47 |
| ▸ | CRHBP | P24387 | 2/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192138 | 0.81 | MAPT (0.58) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL7118162 | 0.80 | MAPT (0.58) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL12338884 | 0.75 | MEN1 (0.83) | LMNASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL9589707 | 0.73 | NPC1 (0.49) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL7126561 | 0.72 | MAPT (0.72) | LMNASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL27676573 | 0.72 | FFAR1 (0.80) | LMNASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL31315570 | 0.72 | FFAR1 (0.80) | LMNASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL5149578 | 0.71 | MEN1 (0.55) | LMNASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL8533619 | 0.70 | KMT2A (0.60) | LMNASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL14567941 | 0.69 | MAPT (0.74) | LMNASMN1; SMN2MAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220832-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001023347-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-04-05 | — | — | WO | disclosed |