Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 20/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160952 | 1.00 | HTR7 (1.00) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6157739 | 0.99 | HTR7 (0.98) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6159564 | 0.97 | HTR7 (0.95) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6158309 | 0.94 | HTR7 (0.88) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6157832 | 0.91 | HTR7 (0.84) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6159368 | 0.88 | HTR7 (1.00) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6161449 | 0.88 | HTR7 (1.00) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL7664123 | 0.86 | HTR7 (0.82) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6158073 | 0.85 | HTR7 (1.00) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6159242 | 0.85 | HTR7 (1.00) | HTR7HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407112-B1 | 2A,3,4,5-TETRAHYDRO-1H-BENZ(CD)INDOL-2-ONE DERIVATIVES; 5-HYDROXYTRYPTAMINE AGONISTS; SLEEP, CIRCADIAN RHYTHYM, BIPOLAR, AND PSYCHOLOGICAL DISORDER TREATMENT | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1081136-A1 | OPTICALLY ACTIVE TETRAHYDROBENZINDOLE DERIVATIVES | Meiji Seika Kaisha, Ltd. (JP) | 2001-03-07 | — | — | EP | disclosed |