Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | AXL | P30530 | 2/20 | 0.43 |
| ▸ | FLT4 | P35916 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | CLK2 | P49760 | 2/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.43 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.43 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.43 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.43 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582563 | 0.89 | MCHR1 (0.58) | MCHR1TRPV1KCNQ3KCNQ2 | |
| SCHEMBL5582718 | 0.84 | MCHR1 (0.71) | MCHR1KCNQ3KCNQ2 | |
| SCHEMBL5582684 | 0.76 | MCHR1 (0.76) | MCHR1 | |
| SCHEMBL5582702 | 0.72 | MCHR1 (0.82) | MCHR1 | |
| SCHEMBL7657444 | 0.72 | MCHR1 (0.45) | MCHR1KDM4EALDH1A1MAPT | |
| SCHEMBL5994627 | 0.68 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL23226736 | 0.67 | DEGS1 (0.64) | KDM4EALDH1A1MAPT | |
| SCHEMBL5582611 | 0.67 | MCHR1 (0.80) | MCHR1 | |
| SCHEMBL5583904 | 0.66 | MCHR1 (0.69) | MCHR1 | |
| SCHEMBL5582546 | 0.66 | MCHR1 (0.80) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218336-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| WO-2001021577-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | claimed |
| EP-1218336-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021577-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | disclosed |