SCHEMBL7657578

SCHEMBL7657578

CC1=CC(N(C(=O)COc2nc3cc(C)ccc3o2)C(C)C)=CC(C)(C)C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.35
RAB9A P51151 5/20 0.35
ALDH1A1 P00352 5/20 0.35
HPGD P15428 4/20 0.35
HSD17B10 Q99714 4/20 0.35
NPC1 O15118 4/20 0.35
MAPK1 P28482 3/20 0.35
KDM4E B2RXH2 3/20 0.35
GAA P10253 3/20 0.35
MAPT P10636 8/20 0.33
AGPAT2 O15120 4/20 0.32
CETP P11597 1/20 0.32
CEPT1 Q9Y6K0 1/20 0.32
TP53 P04637 5/20 0.32
TSHR P16473 2/20 0.32
CASP3 P42574 2/20 0.32
SENP8 Q96LD8 2/20 0.32
SENP7 Q9BQF6 2/20 0.32
SENP6 Q9GZR1 2/20 0.32
PPARD Q03181 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7656128 0.91 ANO1 (0.37) SMN1; SMN2RAB9AALDH1A1MAPTAGPAT2
SCHEMBL7654799 0.89 KMT2A (0.35) SMN1; SMN2RAB9AALDH1A1NPC1KDM4E
SCHEMBL7661965 0.88 AGPAT2 (0.37) SMN1; SMN2RAB9AALDH1A1HPGDHSD17B10
SCHEMBL7660058 0.86 POLQ (0.35) SMN1; SMN2RAB9AALDH1A1HPGDHSD17B10
SCHEMBL7654363 0.86 RAB9A (0.35) SMN1; SMN2RAB9AALDH1A1HPGDHSD17B10
SCHEMBL7662125 0.83 MAPT (0.33) SMN1; SMN2RAB9AALDH1A1HPGDHSD17B10
SCHEMBL8108158 0.80 SMN1; SMN2 (0.35) SMN1; SMN2RAB9AALDH1A1HPGDHSD17B10
SCHEMBL7664341 0.79 ANO1 (0.39) SMN1; SMN2ALDH1A1MAPTAGPAT2CETP
SCHEMBL9403541 0.78 MEN1 (0.48) SMN1; SMN2RAB9AALDH1A1HPGDHSD17B10
SCHEMBL7664996 0.78 ANO1 (0.38) SMN1; SMN2MAPTAGPAT2CETPCEPT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6339042-B1 FOR COMBATING UNDESIRED PLANT GROWTH AMERICAN CYANAMID CO. 2002-01-15 US claimed
US-6339042-B1 FOR COMBATING UNDESIRED PLANT GROWTH AMERICAN CYANAMID CO. 2002-01-15 US disclosed