Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.51 |
| ▸ | FNTB | P49356 | 7/20 | 0.51 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653717 | 0.93 | FNTA (0.51) | FNTAFNTBALDH1A1NPSR1 | |
| SCHEMBL7668699 | 0.92 | FNTA (0.51) | FNTAFNTBPGGT1BALDH1A1NPSR1 | |
| SCHEMBL7662187 | 0.91 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL7662191 | 0.88 | FNTA (0.38) | FNTAFNTBPGGT1B | |
| SCHEMBL7564412 | 0.88 | FNTA (0.49) | FNTAFNTBPGGT1B | |
| SCHEMBL7657870 | 0.87 | FNTA (0.53) | FNTAFNTBPGGT1BALDH1A1NPSR1 | |
| SCHEMBL7562597 | 0.87 | FNTA (0.49) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL7657854 | 0.87 | FNTA (0.49) | FNTAFNTBPGGT1BALDH1A1NPSR1 | |
| SCHEMBL7653580 | 0.85 | FNTA (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL7656299 | 0.85 | FNTA (0.52) | FNTAFNTBALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410539-B1 | ANTICARCINOGENIC AGENTS | ASTRAZENCA UK LIMITED (GB) | 2002-06-25 | — | — | US | claimed |
| EP-1025089-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 2000-08-09 | — | — | EP | claimed |
| WO-1999020612-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-04-29 | — | — | WO | claimed |
| US-6410539-B1 | ANTICARCINOGENIC AGENTS | ASTRAZENCA UK LIMITED (GB) | 2002-06-25 | — | — | US | disclosed |