Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.53 |
| ▸ | FNTB | P49356 | 7/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653727 | 0.93 | FNTA (0.54) | FNTAFNTBALDH1A1NPSR1CYP19A1 | |
| SCHEMBL7658756 | 0.87 | FNTA (0.49) | FNTAFNTBPGGT1BALDH1A1CYP19A1 | |
| SCHEMBL7657859 | 0.87 | FNTA (0.51) | FNTAFNTBPGGT1BALDH1A1NPSR1 | |
| SCHEMBL7609223 | 0.86 | FNTA (0.52) | FNTAFNTBPGGT1BALDH1A1NPSR1 | |
| SCHEMBL7668699 | 0.86 | FNTA (0.51) | FNTAFNTBPGGT1BALDH1A1NPSR1 | |
| SCHEMBL7657854 | 0.85 | FNTA (0.49) | FNTAFNTBPGGT1BALDH1A1NPSR1 | |
| SCHEMBL7562597 | 0.84 | FNTA (0.49) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL7564412 | 0.83 | FNTA (0.49) | FNTAFNTBPGGT1B | |
| SCHEMBL7662201 | 0.83 | FNTA (0.35) | FNTAFNTBPGGT1BCYP19A1 | |
| SCHEMBL8187004 | 0.83 | FNTA (0.53) | FNTAFNTBALDH1A1NPSR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410539-B1 | ANTICARCINOGENIC AGENTS | ASTRAZENCA UK LIMITED (GB) | 2002-06-25 | — | — | US | claimed |
| EP-1025089-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 2000-08-09 | — | — | EP | claimed |
| WO-1999020612-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-04-29 | — | — | WO | claimed |
| US-6410539-B1 | ANTICARCINOGENIC AGENTS | ASTRAZENCA UK LIMITED (GB) | 2002-06-25 | — | — | US | disclosed |
| EP-1025089-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999020612-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-04-29 | — | — | WO | disclosed |