⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647837 | 0.67 | — | — | |
| SCHEMBL121542 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL10924919 | 0.65 | — | — | |
| SCHEMBL9612274 | 0.62 | — | — | |
| Barbituric Acid SCHEMBL38707 | 0.59 | — | — | |
| SCHEMBL4420485 | 0.59 | — | — | |
| Barbituric Acid SCHEMBL4560317 | 0.59 | ALDH1A1 (0.55) | — | |
| Barbituric Acid SCHEMBL9941322 | 0.59 | — | — | |
| Barbituric Acid SCHEMBL1974368 | 0.57 | ALDH1A1 (0.52) | — | |
| SCHEMBL11315691 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059451-B1 | 1,2,6-THIADIAZINE-3,5-DIONE-1,1 DIOXIDES AND THEIR USE | ESPE Fabrik Pharmazeutischer Präparate GmbH (DE) | 1985-07-31 | — | — | EP | claimed |
| US-20230075856-A1 | CYCLIC SULFAMIDE COMPOUNDS FOR TREATMENT OF HBV | ASSEMBLY BIOSCIENCES INC (US) | 2023-03-09 | — | — | US | disclosed |
| US-6472396-B1 | Barbituric acid derivatives, processes for their production and pharmaceutical agents containing these compounds | ROCHE DIAGNOSTICS GMBH (DE) | 2002-10-29 | — | — | US | disclosed |
| US-6110924-A | MATRIX METALLOPROTEASE INHIBITORS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-08-29 | — | — | US | disclosed |
| EP-0869947-A1 | NEW BARBITURIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023465-A1 | NEW BARBITURIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-07-03 | — | — | WO | disclosed |
| EP-0232364-A4 | SUBSTITUTED SACCHARIN COMPOUNDS AND CURABLE COMPOSITIONS CONTAINING SAME. | LOCTITE CORP (US) | 1990-05-14 | — | — | EP | disclosed |
| EP-0232364-A1 | SUBSTITUTED SACCHARIN COMPOUNDS AND CURABLE COMPOSITIONS CONTAINING SAME. | LOCTITE CORP (US) | 1987-08-19 | — | — | EP | disclosed |
| WO-1987000536-A1 | SUBSTITUTED SACCHARIN COMPOUNDS AND CURABLE COMPOSITIONS CONTAINING SAME | LOCTITE CORPORATION (US) | 1987-01-29 | — | — | WO | disclosed |
| EP-0059451-B1 | 1,2,6-THIADIAZINE-3,5-DIONE-1,1 DIOXIDES AND THEIR USE | ESPE Fabrik Pharmazeutischer Präparate GmbH (DE) | 1985-07-31 | — | — | EP | disclosed |
| EP-0059451-A1 | 1,2,6-Thiadiazine-3,5-dione-1,1 dioxides and their use | ESPE Fabrik Pharmazeutischer Präparate GmbH (DE) | 1982-09-08 | — | — | EP | disclosed |
| US-4256819-A | MEROCYANINES | EASTMAN KODAK COMPANY (US) | 1981-03-17 | — | — | US | disclosed |