Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811941 | 0.85 | ALDH1A1 (0.74) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7165775 | 0.78 | MAPT (0.67) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6811057 | 0.77 | MAPT (0.71) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6814781 | 0.77 | ALDH1A1 (0.66) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6811000 | 0.77 | ALDH1A1 (0.63) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6814587 | 0.77 | ALDH1A1 (0.59) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6815568 | 0.76 | ALDH1A1 (0.69) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6819661 | 0.76 | ALDH1A1 (0.66) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5450055 | 0.76 | ALDH1A1 (0.68) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5452833 | 0.76 | ALDH1A1 (0.64) | MAPTALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407249-B1 | COMPOUNDS CONTAINING FURAN RING STRUCTURE | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |
| US-6207715-B1 | USEFUL IN THERAPY OF DISEASES ASSOCIATED WITH HERPES VIRUSES INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES-6 AND -7, AND KAPOSI HERPES VIRUS | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-27 | — | — | US | disclosed |