Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664103 | 0.90 | F10 (0.62) | F2F10MRGPRX4PRSS1PRSS2 | |
| SCHEMBL7719048 | 0.89 | F2 (0.66) | F2F10MRGPRX4PRSS1 | |
| SCHEMBL7668854 | 0.88 | F2 (0.51) | F2F10MRGPRX4PRSS1PRSS2 | |
| SCHEMBL7665464 | 0.88 | MRGPRX4 (0.54) | F2F10MRGPRX4PRSS1PRSS2 | |
| SCHEMBL7668085 | 0.85 | F2 (0.58) | F2F10MRGPRX4 | |
| SCHEMBL7660549 | 0.85 | F2 (0.52) | F2F10MRGPRX4LMNA | |
| SCHEMBL7666941 | 0.84 | F2 (0.60) | F2F10MRGPRX4PRSS1PRSS2 | |
| SCHEMBL7664269 | 0.84 | F2 (0.60) | F2F10MRGPRX4PRSS1 | |
| SCHEMBL7665912 | 0.83 | MRGPRX4 (0.48) | MRGPRX4KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL8072787 | 0.82 | F2 (0.49) | F2F10MRGPRX4NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |