Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.67 |
| ▸ | CTSK | P43235 | 6/20 | 0.67 |
| ▸ | CTSB | P07858 | 5/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | FCER2 | P06734 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331930 | 0.91 | CTSS (0.69) | CTSSCTSKCTSBPTPN1ACE | |
| SCHEMBL7655882 | 0.91 | CTSS (0.69) | CTSSCTSKCTSBPTPN1ACE | |
| SCHEMBL8740509 | 0.91 | CTSS (0.69) | CTSSCTSKCTSBPTPN1ACE | |
| SCHEMBL7282281 | 0.89 | CTSS (0.71) | CTSSCTSKCTSBPTPN1ACE | |
| SCHEMBL29397962 | 0.87 | CTSS (0.74) | CTSSCTSKCTSBPTPN1ACE | |
| SCHEMBL3821361 | 0.87 | CTSS (0.74) | CTSSCTSKCTSBPTPN1ACE | |
| SCHEMBL29401906 | 0.87 | CTSS (0.74) | CTSSCTSKCTSBPTPN1ACE | |
| SCHEMBL29436862 | 0.87 | CTSS (0.74) | CTSSCTSKCTSBPTPN1ACE | |
| SCHEMBL1519731 | 0.87 | CTSS (0.74) | CTSSCTSKCTSBPTPN1ACE | |
| SCHEMBL29481445 | 0.87 | CTSS (0.74) | CTSSCTSKCTSBPTPN1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1225471-C | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 2005-11-02 | — | — | CN | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| CN-1176645-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1998-03-18 | — | — | CN | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |