Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656080 | 0.94 | P2RX7 (0.71) | P2RX7 | |
| SCHEMBL30341704 | 0.94 | P2RX7 (0.71) | P2RX7 | |
| Hydrochloric Acid SCHEMBL29453510 | 0.93 | P2RX7 (0.70) | P2RX7 | |
| SCHEMBL7528044 | 0.90 | P2RX7 (0.63) | P2RX7 | |
| SCHEMBL7669060 | 0.89 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL7663299 | 0.87 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL7557040 | 0.87 | P2RX7 (0.78) | P2RX7 | |
| SCHEMBL7663091 | 0.87 | P2RX7 (0.61) | P2RX7 | |
| SCHEMBL7556108 | 0.86 | P2RX7 (0.70) | P2RX7 | |
| Hydrochloric Acid SCHEMBL7658580 | 0.85 | P2RX7 (0.69) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492355-B1 | Adamantane derivatives | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | claimed |
| US-6492355-B1 | Adamantane derivatives | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | disclosed |