Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | F13A1 | P00488 | 1/20 | 0.58 |
| ▸ | TGM2 | P21980 | 1/20 | 0.58 |
| ▸ | TGM1 | P22735 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970912 | 0.93 | MEN1 (0.76) | L3MBTL1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL379160 | 0.93 | MEN1 (0.76) | L3MBTL1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL4814264 | 0.93 | MEN1 (0.76) | L3MBTL1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL7393652 | 0.93 | MEN1 (0.76) | L3MBTL1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL15011579 | 0.91 | MEN1 (0.73) | L3MBTL1MEN1KMT2ANPSR1SMN1; SMN2 | |
| Bicarbonate SCHEMBL4357688 | 0.91 | MEN1 (0.73) | L3MBTL1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL31439570 | 0.91 | L3MBTL1 (0.62) | L3MBTL1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL953327 | 0.89 | MEN1 (0.62) | L3MBTL1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL10243152 | 0.89 | MEN1 (0.62) | L3MBTL1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL15709327 | 0.89 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527270-B | Medical intermediate of PROTAC molecule targeting monoacylglycerol lipase, preparation method and application | 河南大学 | 2024-03-01 | — | — | CN | claimed |
| CN-113527270-B | Medical intermediate of PROTAC molecule targeting monoacylglycerol lipase, preparation method and application | 河南大学 | 2024-03-01 | — | — | CN | disclosed |
| US-6335341-B1 | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2002-01-01 | — | — | US | disclosed |
| EP-1000057-A1 | PYRIDYL- AND PYRIMIDYL-HETEROCYCLIC COMPOUNDS INHIBITING OXIDO SQUALENE-CYCLASE | AstraZeneca UK Limited (GB) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006395-A1 | PYRIDYL- AND PYRIMIDYL-HETEROCYCLIC COMPOUNDS INHIBITING OXIDO SQUALENE-CYCLASE | ZENECA LIMITED (GB) | 1999-02-11 | — | — | WO | disclosed |