Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229239 | 0.79 | TP53 (0.41) | TP53MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5189407 | 0.78 | KDM5A (0.40) | TP53MEN1KMT2AKDM4EPOLB | |
| SCHEMBL2485564 | 0.76 | MEN1 (0.45) | TP53MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL7865102 | 0.75 | MEN1 (0.38) | TP53MEN1KMT2AKDM4EPOLB | |
| SCHEMBL18751640 | 0.75 | TP53 (0.51) | TP53MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7861688 | 0.74 | MEN1 (0.39) | TP53MEN1KMT2AKDM4EPOLB | |
| SCHEMBL7615932 | 0.72 | MAPT (0.39) | KDM4ERAB9ATDP1HSD17B10GSK3B | |
| SCHEMBL15200926 | 0.70 | MEN1 (0.41) | TP53MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5788461 | 0.70 | MEN1 (0.40) | TP53MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL12009980 | 0.69 | GRIN2D (0.43) | TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097139-B1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2002-12-04 | — | — | EP | claimed |