Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860205 | 0.92 | MEN1 (0.42) | MEN1KMT2ATP53LMNAMAPK1 | |
| SCHEMBL7861641 | 0.87 | TSHR (0.38) | MEN1KMT2ACYP1A2CYP3A4GAA | |
| SCHEMBL7862448 | 0.85 | KMT2A (0.38) | MEN1KMT2APOLBLMNAKDM4E | |
| SCHEMBL7861688 | 0.82 | MEN1 (0.39) | MEN1KMT2ACYP1A2CYP3A4GAA | |
| SCHEMBL7861633 | 0.78 | KDM4E (0.37) | CYP3A4KDM4ERAB9ATDP1KDM5A | |
| SCHEMBL7862451 | 0.78 | TSHR (0.38) | MEN1KMT2ACYP1A2CYP3A4GAA | |
| SCHEMBL321543 | 0.76 | MEN1 (0.45) | MEN1KMT2APOLBTP53LMNA | |
| SCHEMBL7559771 | 0.76 | MEN1 (0.50) | MEN1KMT2ATP53LMNAMAPK1 | |
| SCHEMBL7750180 | 0.76 | MEN1 (0.45) | MEN1KMT2ATP53LMNAMAPK1 | |
| SCHEMBL7861387 | 0.76 | KDM5A (0.50) | MEN1KMT2AGAAPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097139-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003992-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2000-01-27 | — | — | WO | disclosed |