Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111073 | 0.86 | PTGIR (0.49) | PTGIRHPGDKDM4EALDH1A1PTGDR | |
| SCHEMBL7108726 | 0.81 | DDB1 (0.40) | DDB1CRBNPTGIRHPGDKDM4E | |
| SCHEMBL7104410 | 0.81 | DDB1 (0.40) | DDB1CRBNPTGIRHPGDKDM4E | |
| SCHEMBL7654170 | 0.78 | PTGIR (0.52) | PTGIRPTGDRPTGER1PTGER3L3MBTL1 | |
| SCHEMBL7104442 | 0.77 | DDB1 (0.52) | DDB1CRBNHPGDKDM4EMEN1 | |
| SCHEMBL7650676 | 0.76 | PTGIR (0.39) | PTGIRKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL7106168 | 0.75 | ATM (0.41) | PTGIRPTGDRNPSR1L3MBTL1TDP1 | |
| SCHEMBL7106164 | 0.75 | L3MBTL1 (0.41) | PTGIRMEN1ALDH1A1TSHRKMT2A | |
| Tert-Butylamine SCHEMBL7655093 | 0.73 | PTGIR (0.44) | PTGIRHPGDKDM4EALDH1A1PTGDR | |
| SCHEMBL22656552 | 0.72 | POLB (0.50) | DDB1CRBNHPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335459-B1 | PROSTAGLANDIN I2 RECEPTOR MODULATORS; TREATING TISSUE NECROSIS, PREMATURE UTERINE CONTRACTION, GASTRIC ULCERATION, SEXUAL DYSFUNCTION, MENSTRUAL PAIN AND IMPROPER WOUND HEALING, IMMUNOREGULATION, PLATELET AGGREGATION OR NEUTROPHIL FUNCTION | SYNTEX (U.S.A.) LLC | 2002-01-01 | — | — | US | disclosed |