Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658964 | 1.00 | NR1H4 (0.49) | NR1H4KMT2AMEN1PTGS2HCAR2 | |
| SCHEMBL6345435 | 0.88 | GLO1 (0.48) | NR1H4KMT2AMEN1PTGS2HCAR2 | |
| SCHEMBL6345437 | 0.88 | GLO1 (0.48) | NR1H4KMT2AMEN1PTGS2HCAR2 | |
| SCHEMBL11462566 | 0.86 | KMT2A (0.57) | NR1H4KMT2AMEN1PTGS2GLO1 | |
| SCHEMBL11552505 | 0.86 | KMT2A (0.57) | NR1H4KMT2AMEN1PTGS2GLO1 | |
| SCHEMBL6931126 | 0.83 | HCAR2 (0.40) | NR1H4KMT2AMEN1PTGS2HCAR2 | |
| SCHEMBL6931128 | 0.83 | HCAR2 (0.40) | NR1H4KMT2AMEN1PTGS2HCAR2 | |
| SCHEMBL11742324 | 0.83 | GLO1 (0.64) | NR1H4KMT2AMEN1GLO1ALDH1A1 | |
| SCHEMBL6643038 | 0.80 | NR1H4 (0.47) | NR1H4KMT2AMEN1HCAR2ALDH1A1 | |
| SCHEMBL6643040 | 0.80 | NR1H4 (0.47) | NR1H4KMT2AMEN1HCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350762-B1 | SELECTIVELY INHIBIT THE ACTION OF N-TYPE CALCIUM CHANNEL; | AJINOMOTO CO., INC. (JP) | 2002-02-26 | — | — | US | disclosed |