Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223395 | 1.00 | HIF1A (0.45) | HIF1AALDH1A1LMNAHPGDPOLB | |
| SCHEMBL7223391 | 1.00 | HIF1A (0.45) | HIF1AALDH1A1LMNAHPGDPOLB | |
| SCHEMBL27463792 | 0.89 | HIF1A (0.44) | HIF1AALDH1A1LMNAHPGDPOLB | |
| SCHEMBL6721998 | 0.87 | HIF1A (0.46) | HIF1AALDH1A1LMNAHPGDPOLB | |
| SCHEMBL6719570 | 0.87 | HIF1A (0.46) | HIF1AALDH1A1LMNAHPGDPOLB | |
| SCHEMBL6719571 | 0.87 | HIF1A (0.46) | HIF1AALDH1A1LMNAHPGDPOLB | |
| Methyl Alcohol SCHEMBL8502229 | 0.86 | HIF1A (0.45) | HIF1AALDH1A1LMNAHPGDPOLB | |
| Methyl Alcohol SCHEMBL8502232 | 0.86 | HIF1A (0.45) | HIF1AALDH1A1LMNAHPGDPOLB | |
| SCHEMBL7952561 | 0.86 | HIF1A (0.45) | HIF1AALDH1A1LMNAHPGDPOLB | |
| SCHEMBL7952558 | 0.86 | HIF1A (0.45) | HIF1AALDH1A1LMNAHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465457-B1 | CONTROLLING PATHOGENS ON PLANTS OR SEEDS | ZENECA LIMITED (GB) | 2002-10-15 | — | — | US | disclosed |
| US-5939563-A | FUNGICIDES | ZENECA LIMITED (GB) | 1999-08-17 | — | — | US | disclosed |
| US-5777162-A | Intermediates for the preparation of fungicides | ZENECA LIMITED (GB) | 1998-07-07 | — | — | US | disclosed |
| US-5693859-A | REACTING ORTHO-SUBSTITUTED PHENYL ALPHA-KETO ACID HALIDE WITH AN AMINE YIELDS SUBSTITUTED PHENYL ALPHA-KETAMIDE | SHIONOGI & CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| US-5585513-A | CHEMICAL INTERMEDIATES | ZENECA LIMITED (GB) | 1996-12-17 | — | — | US | disclosed |
| EP-0711751-A1 | Process for the preparation of intermediates for oxime ether- or 2-phenyl-3-methyl propenoate-fungicides | ZENECA LIMITED (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1993007116-A1 | FUNGICIDES | ZENECA LIMITED (GB) | 1993-04-15 | — | — | WO | disclosed |