Sugi Predict

Sugi Predict / Compounds / SCHEMBL6721998

SCHEMBL6721998

SCHEMBL6721998

CNC(=O)/C(=N\OC)c1ccccc1CO

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 9/20 0.46
▸ LMNA P02545 2/20 0.41
▸ HPGD P15428 2/20 0.41
▸ GAA P10253 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ NPC1 O15118 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.37
▸ CYP2C9 P11712 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ ATM Q13315 1/20 0.35
▸ PLK1 P53350 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6719571 1.00 HIF1A (0.46) HIF1ALMNAHPGDGAAL3MBTL1
SCHEMBL6719570 1.00 HIF1A (0.46) HIF1ALMNAHPGDGAAL3MBTL1
Methyl Alcohol SCHEMBL8502232 0.99 HIF1A (0.45) HIF1ALMNAHPGDGAAL3MBTL1
Methyl Alcohol SCHEMBL8502229 0.99 HIF1A (0.45) HIF1ALMNAHPGDGAAL3MBTL1
SCHEMBL7658977 0.87 HIF1A (0.45) HIF1ALMNAHPGDALDH1A1CYP2C9
SCHEMBL7223395 0.87 HIF1A (0.45) HIF1ALMNAHPGDALDH1A1CYP2C9
SCHEMBL7952558 0.87 HIF1A (0.45) HIF1ALMNAHPGDALDH1A1KDM4E
SCHEMBL7223391 0.87 HIF1A (0.45) HIF1ALMNAHPGDALDH1A1CYP2C9
SCHEMBL7952561 0.87 HIF1A (0.45) HIF1ALMNAHPGDALDH1A1KDM4E
SCHEMBL7843287 0.86 HIF1A (0.44) HIF1ALMNAHPGDGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734143-B2 2-methoxyimino-2(pyridinyloxymethyl)phenyl acetamides useful as fungicides DOW AGROSCIENCES LLC 2004-05-11 — — US disclosed
US-20040063763-A1 2-METHOXYIMINO-2(PYRIDINYLOXYMETHYL)PHENYL ACETAMIDES USEFUL AS FUNGICIDES KIRBY NEIL VINCENT (US) 2004-04-01 — — US disclosed
US-6465457-B1 CONTROLLING PATHOGENS ON PLANTS OR SEEDS ZENECA LIMITED (GB) 2002-10-15 — — US disclosed
US-20020115865-A1 2-methoxyimino-2- (pyridinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring CANADA EMILY J (US) 2002-08-22 — — US disclosed
US-6436963-B1 FUNGICIDES DOW AGROSCIENCES LLC 2002-08-20 — — US disclosed
US-6432951-B1 FUNGICIDES DOW AGROSCIENCES LLC 2002-08-13 — — US disclosed
US-6432990-B1 FUNGICIDES DOW AGROSCIENCES LLC 2002-08-13 — — US disclosed
US-6369083-B1 2-methoxyimino-2 (pyrinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring DOW AGROSCIENCES LLC 2002-04-09 — — US disclosed
US-20020035259-A1 2-methoxyimino-2-(pyridinyloxymethyl)phenyl acetamides with (derivatised) hydroxyalkyl derivatives on the pyridine ring CANADA EMILY J (US) 2002-03-21 — — US disclosed
US-20020035257-A1 2-methoxyimino-2-(pyridinyloxymethyl) phenyl acetamides with (derivatised) hydroxyalkyl derivatives on the pyridine ring CANADA EMILY J (US) 2002-03-21 — — US disclosed
EP-0801054-A1 PROCESS FOR PRODUCING 2-(2-HYDROXYMETHYLPHENYL)ACETAMIDE DERIVATIVE AND INTERMEDIATE FOR THE PRODUCTION THEREOF SHIONOGI & CO., LTD. (JP) 1997-10-15 — — EP disclosed
EP-0781764-A1 PROCESS FOR PRODUCING ALKOXYIMINOACETAMIDE DERIVATIVE SHIONOGI & CO., LTD. (JP) 1997-07-02 — — EP disclosed
US-5585513-A CHEMICAL INTERMEDIATES ZENECA LIMITED (GB) 1996-12-17 — — US disclosed
US-5548078-A FOR AGRICULTURE SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1996-08-20 — — US disclosed
EP-0711751-A1 Process for the preparation of intermediates for oxime ether- or 2-phenyl-3-methyl propenoate-fungicides ZENECA LIMITED (GB) 1996-05-15 — — EP disclosed
US-5401877-A Agricultural fungicide SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1995-03-28 — — US disclosed
US-5371222-A Intermediates SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-12-06 — — US disclosed
US-5371223-A Controlling phytopathogens SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-12-06 — — US disclosed
WO-1993007116-A1 FUNGICIDES ZENECA LIMITED (GB) 1993-04-15 — — WO disclosed
US-5185342-A ALKOXYIMINOACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1993-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035259-A1 2-methoxyimino-2-(pyridinyloxymethyl)phenyl acetamides with (derivatised) hydroxyalkyl derivatives on the pyridine ring AADAC, CYP1A2, NAAA HIF1A 4113/4885LMNA 2320/4885HPGD 999/4885
US-20020035257-A1 2-methoxyimino-2-(pyridinyloxymethyl) phenyl acetamides with (derivatised) hydroxyalkyl derivatives on the pyridine ring AADAC, CYP1A2, NAAA HIF1A 4113/4885LMNA 2320/4885HPGD 999/4885
US-20020115865-A1 2-methoxyimino-2- (pyridinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring AADAC, MIDEAS, CNPY2 HIF1A 4745/4885LMNA 2114/4885HPGD 2662/4885
US-20040063763-A1 2-METHOXYIMINO-2(PYRIDINYLOXYMETHYL)PHENYL ACETAMIDES USEFUL AS FUNGICIDES DPYSL2, AADAC, PYCR1 HIF1A 4440/4885LMNA 1851/4885HPGD 2160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.