Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PPM1D | O15297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772886 | 1.00 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL25758895 | 1.00 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL25758875 | 1.00 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL11548963 | 1.00 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL7441811 | 1.00 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL14440399 | 1.00 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL14440425 | 1.00 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL7679245 | 0.87 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL6772879 | 0.84 | — | — | |
| SCHEMBL17694215 | 0.84 | CA12 (0.34) | CA12CA9CA1CA2PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262215-B2 | N-carbacycle monosubstituted indolocarbazoles as protein kinase inhibitors | NAD AG (DE) | 2007-08-28 | — | — | US | disclosed |
| US-6492406-B1 | PROTEIN KINASE C INHIBITORS; ANTIINFLAMMATORY AND IMMUNO-SUPPRESSIVE AGENTS | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | disclosed |
| EP-0873340-B1 | HETEROCYCLIC SUBSTITUTED CYCLOPENTANE COMPOUNDS | ABBOTT LAB (US) | 2001-11-21 | — | — | EP | disclosed |
| US-6143749-A | Heterocyclic substituted cyclopentane compounds | ABBOTT LABORATORIES (US) | 2000-11-07 | — | — | US | disclosed |
| EP-0790981-B1 | ARYLOXYCYCLOALKENYL AND ARYLOXYIMINOCYCLOALKENYLHYDROXYUREAS AS 5-LIPOXYGENASE INHIBITORS | PFIZER (US) | 1999-09-08 | — | — | EP | disclosed |
| US-5798383-A | Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas | PFIZER INC. (US) | 1998-08-25 | — | — | US | disclosed |
| US-5665721-A | ADENOSINE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 1997-09-09 | — | — | US | disclosed |
| WO-1996040686-A1 | HETEROCYCLIC SUBSTITUTED CYCLOPENTANE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | disclosed |