Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PPM1D | O15297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17694215 | 0.94 | CA12 (0.34) | CA12CA9CA1CA2PREP | |
| SCHEMBL11548963 | 0.87 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL25758895 | 0.87 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL25758875 | 0.87 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL7659117 | 0.87 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL14440425 | 0.87 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL7441811 | 0.87 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL6772886 | 0.87 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL14440399 | 0.87 | CA12 (0.35) | CA12CA9CA1CA2PREP | |
| SCHEMBL8354298 | 0.80 | CA12 (0.42) | CA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346625-B1 | ENZYME INHIBITORS FOR PROTEIN KINASES | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | disclosed |