Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662376 | 0.91 | PPARG (0.48) | PPARGPPARDPPARA | |
| SCHEMBL5208481 | 0.91 | PPARG (0.53) | PPARGPPARDPPARA | |
| SCHEMBL5208431 | 0.88 | PPARG (0.57) | PPARGPPARDPPARA | |
| SCHEMBL14621683 | 0.86 | PPARG (0.48) | PPARGPPARDPPARA | |
| SCHEMBL5211565 | 0.77 | PPARG (0.61) | PPARGPPARDPPARA | |
| SCHEMBL5208872 | 0.76 | GRM2 (0.59) | PPARGPPARDPPARA | |
| SCHEMBL7661972 | 0.75 | PPARG (0.49) | PPARGPPARDPPARA | |
| SCHEMBL7669088 | 0.73 | PPARG (0.49) | PPARGPPARDPPARA | |
| SCHEMBL7459290 | 0.72 | PPARG (0.40) | PPARGPPARDPPARA | |
| SCHEMBL7663361 | 0.71 | PPARG (0.40) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399640-B1 | ANTIDIABETIC AGENTS; ANTICHOLESTEROL AGENTS | MERCK & CO., INC. | 2002-06-04 | — | — | US | claimed |
| US-6399640-B1 | ANTIDIABETIC AGENTS; ANTICHOLESTEROL AGENTS | MERCK & CO., INC. | 2002-06-04 | — | — | US | disclosed |