Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 16/20 | 1.00 |
| ▸ | TOP2A | P11388 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PDE1A | P54750 | 1/20 | 0.48 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30637547 | 1.00 | ALOX5 (1.00) | ALOX5TOP2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL29582148 | 1.00 | ALOX5 (1.00) | ALOX5TOP2AKDM4EMEN1ALDH1A1 | |
| Retrojusticidin B SCHEMBL28070386 | 0.88 | ALOX5 (1.00) | ALOX5TOP2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL7659431 | 0.85 | ALOX5 (0.79) | ALOX5TOP2AKDM4EMEN1ALDH1A1 | |
| Helioxanthin SCHEMBL2960321 | 0.82 | ALOX5 (0.70) | ALOX5TOP2AKDM4EMEN1ALDH1A1 | |
| Helioxanthin SCHEMBL29623971 | 0.82 | ALOX5 (0.70) | ALOX5TOP2AKDM4EMEN1ALDH1A1 | |
| Taiwanin C SCHEMBL27920039 | 0.80 | ALOX5 (1.00) | ALOX5TOP2AKDM4EMEN1ALDH1A1 | |
| Taiwanin C SCHEMBL31237252 | 0.80 | ALOX5 (1.00) | ALOX5TOP2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8085088 | 0.79 | ALOX5 (1.00) | ALOX5TOP2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8085298 | 0.78 | ALOX5 (0.73) | ALOX5TOP2AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |