Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 14/20 | 0.75 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028739 | 0.88 | PDGFRB (0.75) | PDGFRBFLT3 | |
| SCHEMBL7659416 | 0.86 | PDGFRB (1.00) | PDGFRBPI4KBFLT3 | |
| SCHEMBL7666881 | 0.82 | TRPV1 (0.53) | PDGFRBPI4KBKCNH2FLT3 | |
| SCHEMBL1028741 | 0.77 | PDGFRB (1.00) | PDGFRBFLT3 | |
| SCHEMBL2921452 | 0.74 | PDGFRB (0.74) | PDGFRBFLT3 | |
| SCHEMBL2278769 | 0.74 | PDGFRB (1.00) | PDGFRBFLT3 | |
| SCHEMBL1031644 | 0.74 | PDGFRB (0.64) | PDGFRBFLT3 | |
| SCHEMBL7655638 | 0.73 | PDGFRB (0.66) | PDGFRBFLT3 | |
| SCHEMBL2912640 | 0.73 | PDGFRB (1.00) | PDGFRBFLT3 | |
| SCHEMBL2924358 | 0.72 | PDGFRB (1.00) | PDGFRBFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423716-B1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |