SCHEMBL765960

SCHEMBL765960

C[SiH2]C=C(N(C)C)N(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232019 0.70
SCHEMBL11108393 0.62 KDM4E (0.33)
SCHEMBL2104078 0.57
SCHEMBL20808177 0.57
SCHEMBL1061564 0.57
SCHEMBL1055301 0.53
SCHEMBL610283 0.53
SCHEMBL19184608 0.47 KDM4E (0.33)
SCHEMBL697806 0.46
SCHEMBL968099 0.46

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621375-B Rubber with backbone and end-group functionalization 固特异轮胎和橡胶公司 2024-06-18 CN disclosed
US-10351636-B2 Processes for preparing aminosilane functionalized polymers BRIDGESTONE CORPORATION (JP) 2019-07-16 US disclosed
US-9676874-B2 Processes for preparing aminosilane functionalized polymers BRIDGESTONE CORPORATION (JP) 2017-06-13 US disclosed
US-20160152756-A1 PROCESSES FOR PREPARING AMINOSILANE FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2016-06-02 US disclosed
US-9255158-B2 Aminosilane initiators, functionalized polymers prepared therefrom and related processes BRIDGESTONE CORPORATION (JP) 2016-02-09 US disclosed
US-20150099852-A1 AMINOSILANE INITIATORS, FUNCTIONALIZED POLYMERS PREPARED THEREFROM AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2015-04-09 US disclosed
US-8916665-B2 Aminosilane initiators and functionalized polymers prepared therefrom BRIDGESTONE CORPORATION (JP) 2014-12-23 US disclosed
EP-2658727-B1 AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM BRIDGESTONE CORP (JP) 2014-12-03 EP disclosed
US-8846844-B2 Crosslinkable polyolefin composition comprising silane groups forming an acid or a base upon hydrolysation BOREALIS AG (AT) 2014-09-30 US disclosed
EP-2658727-A1 AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM Bridgestone Corporation (JP) 2013-11-06 EP disclosed
US-20130281645-A1 Aminosilane Initiators And Functionalized Polymers Prepared Therefrom BRIDGESTONE CORPORATION (JP) 2013-10-24 US disclosed
WO-2012091753-A1 AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM BRIDGESTONE CORPORATION (JP) 2012-07-05 WO disclosed
US-20120071607-A1 CROSSLINKABLE POLYOLEFIN COMPOSITION COMPRISING SILANE GROUPS FORMING AN ACID OR A BASE UPON HYDROLYSATION BOREALIS AG (AT) 2012-03-22 US disclosed