SCHEMBL7659890

SCHEMBL7659890

CCCCCC1CC(O)c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 1/20 0.41
CYSLTR1 Q9Y271 1/20 0.41
CFTR P13569 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CES2 O00748 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28989845 0.87 CYSLTR2 (0.47) CYSLTR2CYSLTR1CES2
SCHEMBL28664760 0.81 CYSLTR2 (0.40) CYSLTR2CYSLTR1CES2
SCHEMBL28674736 0.81 CYSLTR2 (0.40) CYSLTR2CYSLTR1CES2
SCHEMBL7932142 0.81 CYSLTR2 (0.38) CYSLTR2CYSLTR1
SCHEMBL7936083 0.81 CYSLTR2 (0.38) CYSLTR2CYSLTR1
SCHEMBL28667195 0.81 CYSLTR2 (0.40) CYSLTR2CYSLTR1CES2
SCHEMBL7932145 0.81 CYSLTR2 (0.38) CYSLTR2CYSLTR1
SCHEMBL7646825 0.81 CYSLTR2 (0.38) CYSLTR2CYSLTR1
SCHEMBL7936081 0.81 CYSLTR2 (0.38) CYSLTR2CYSLTR1
SCHEMBL29117075 0.79 CYSLTR2 (0.44) CYSLTR2CYSLTR1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002500211-A 2002-01-08 JP claimed
EP-1044184-A1 SYNTHESIS OF 3-ARYL-1-INDANAMINES Pharm-Eco Laboratoires, Incorporated (US) 2000-10-18 EP claimed
WO-1999035119-A1 SYNTHESIS OF 3-ARYL-1-INDANAMINES PHARM-ECO LABORATORIES, INC. (US) 1999-07-15 WO claimed
EP-1044184-A1 SYNTHESIS OF 3-ARYL-1-INDANAMINES Pharm-Eco Laboratoires, Incorporated (US) 2000-10-18 EP disclosed
WO-1999035119-A1 SYNTHESIS OF 3-ARYL-1-INDANAMINES PHARM-ECO LABORATORIES, INC. (US) 1999-07-15 WO disclosed