Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936081 | 1.00 | CYSLTR2 (0.38) | CYSLTR2CYSLTR1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7936083 | 1.00 | CYSLTR2 (0.38) | CYSLTR2CYSLTR1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7932145 | 1.00 | CYSLTR2 (0.38) | CYSLTR2CYSLTR1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL28989845 | 0.85 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL4557220 | 0.85 | SLC6A2 (0.39) | CYSLTR2CYSLTR1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7659890 | 0.81 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1 | |
| SCHEMBL28664760 | 0.79 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1 | |
| SCHEMBL28674736 | 0.79 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1 | |
| SCHEMBL28667195 | 0.79 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1 | |
| SCHEMBL29117075 | 0.78 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268535-B1 | REACTING BENZENE SUBSTITUTED UNSATURATED CARBOXYLIC ACID IN PRESENCE OF FRIEDEL-CRAFT CATALYST WITH BENZENE COMPOUND TO FORM 3-ARYL-3-PHENYL-1-PROPANOIC ACID REACTING TO FORM 3-ARYL INDAN; REDUCING, REACTING WITH AMINE TO FORM 3-ARYLINDANAMINE | PHARM-ECO LABORATORIES, INC. | 2001-07-31 | — | — | US | disclosed |