Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 15/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661712 | 0.91 | CTSD (0.40) | — | |
| SCHEMBL7671000 | 0.86 | CMA1 (0.41) | CMA1KMT2AKLK5MEN1ATM | |
| SCHEMBL7668502 | 0.86 | CMA1 (0.40) | CMA1KMT2AKLK5MEN1ATM | |
| SCHEMBL7661534 | 0.86 | CMA1 (0.45) | CMA1KMT2AMEN1ATM | |
| SCHEMBL7665089 | 0.85 | CMA1 (0.44) | CMA1KMT2AKLK5MEN1ATM | |
| SCHEMBL7667974 | 0.85 | CMA1 (0.47) | CMA1KMT2AKLK5MEN1ATM | |
| SCHEMBL7667170 | 0.84 | CMA1 (0.48) | CMA1KMT2AKLK5MEN1ATM | |
| SCHEMBL7661645 | 0.83 | CMA1 (0.40) | CMA1KMT2AKLK5MEN1ATM | |
| SCHEMBL7658536 | 0.80 | CMA1 (0.52) | CMA1KMT2AMEN1ATMCTRC | |
| SCHEMBL6347120 | 0.79 | KLK5 (0.49) | KLK5ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |