⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24859001 | 0.79 | — | — | |
| SCHEMBL140950 | 0.75 | TSHR (0.59) | — | |
| SCHEMBL891217 | 0.75 | TSHR (0.46) | — | |
| SCHEMBL17541243 | 0.73 | TSHR (0.44) | — | |
| Water SCHEMBL27837138 | 0.73 | TSHR (0.44) | — | |
| SCHEMBL2211226 | 0.71 | — | — | |
| SCHEMBL348694 | 0.71 | — | — | |
| SCHEMBL25435426 | 0.71 | TSHR (0.43) | — | |
| SCHEMBL20822068 | 0.71 | — | — | |
| SCHEMBL3678577 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344564-B1 | FUNGICIDES | RHONE-POULENC, INC. | 2002-02-05 | — | — | US | claimed |
| US-6018052-A | APPLYING TO CROPS OR THEIR SEEDS TO PREVENT OR CURE FUNGAL DISEASES; STEREOSPECIFIC COMPOUND WITH IMPROVED BIOLOGICAL ACTIVITY | RHONE-POULENC AGROCHIMIE (FR) | 2000-01-25 | — | — | US | claimed |
| US-6002016-A | Fungicidal 2-imidazolin-5-ones and 2-imidazoline-5-thiones | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-14 | — | — | US | claimed |
| US-5650519-A | Optically active 5, 5-disubstituted-3-(mono- or disubstituted amino)-2-thiohydantoin intermediates to fungicidal 2-imidazolin-5-ones | RHONE-POULENC AGROCHIMIE (FR) | 1997-07-22 | — | — | US | claimed |
| US-6344564-B1 | FUNGICIDES | RHONE-POULENC, INC. | 2002-02-05 | — | — | US | disclosed |
| US-6018052-A | APPLYING TO CROPS OR THEIR SEEDS TO PREVENT OR CURE FUNGAL DISEASES; STEREOSPECIFIC COMPOUND WITH IMPROVED BIOLOGICAL ACTIVITY | RHONE-POULENC AGROCHIMIE (FR) | 2000-01-25 | — | — | US | disclosed |
| US-6008370-A | FUNGICIDAL IMIDAZOLINONE AND IMIDAZOLINETHIONE COMPOUNDS FOR USE IN PLANT PROTECTION | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-28 | — | — | US | disclosed |
| US-6002016-A | Fungicidal 2-imidazolin-5-ones and 2-imidazoline-5-thiones | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-14 | — | — | US | disclosed |
| US-5650519-A | Optically active 5, 5-disubstituted-3-(mono- or disubstituted amino)-2-thiohydantoin intermediates to fungicidal 2-imidazolin-5-ones | RHONE-POULENC AGROCHIMIE (FR) | 1997-07-22 | — | — | US | disclosed |
| US-5637729-A | AGRICULTURE | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-10 | — | — | US | disclosed |